SIRE: A versatile toolbox for genome editing

Chromosomal integration of biosynthetic pathways for the production of high‐value chemicals is a necessity to develop industrial strains with a high long‐term stability and a low production variability. Here we present SIRE, Serine Integrase Recombinational Engineering, a novel methodology which combines…

Check our review in Biotechnology Advances: Hidden antibiotics: Where to uncover?

The quest to find novel antibiotics is currently very difficult in a time where antimicrobial resistance is on the rise. By causing 25.000 deaths in the European Union alone, it is the sixth major death cause in the EU. In case…

New article published in Colloids and Interfaces on ‘Expression of Chimeric Cytochrome P450s’

‘Classical’ biosurfactants produced by Starmerella bombicola contain oleic acid as the incorporated hydrophobic group. However, other chain lengths can (to a certain content) be incorporated by feeding the yeast with substrates of alternative chain lengths, be it with a lower efficiency. …