The CARBOSURF project addressed the full exploitation of two very promising types of specialty biochemicals. These include glycolipid biosurfactants (new-to-nature sophorolipids, rhamnolipids, mannosylerythritol lipids (MELs) and xylolipids) as well as specialty carbohydrates with high market interest. These innovative molecules were developed for the food, cosmetic and nutraceutical industry in close cooperation with relevant major Read more about CARBOSURF – Results in Brief published article on CORDIS[…]
As an early Christmas present, our newest book chapter on ‘Microbial Biosurfactants: From Lab to Market’ was published in the CRC Press book on microbial biosurfactants on December 19th. For more information: click here.
The MOOC (Massive Open Online Course) “Biobased Products for a Sustainable (Bio)economy”, in which InBio.be has participated, is starting in January 2019! Enroll now and learn all about sustainable biobased products.
Chromosomal integration of biosynthetic pathways for the production of high‐value chemicals is a necessity to develop industrial strains with a high long‐term stability and a low production variability. Here we present SIRE, Serine Integrase Recombinational Engineering, a novel methodology which combines the ease of recombinase mediated cassette exchange (RMCE) with the selectivity of orthogonal att sites of the Read more about SIRE: A versatile toolbox for genome editing[…]
The quest to find novel antibiotics is currently very difficult in a time where antimicrobial resistance is on the rise. By causing 25.000 deaths in the European Union alone, it is the sixth major death cause in the EU. In case too little novel antibiotics are developed, many surgical procedures will become increasingly risky and the Read more about Check our review in Biotechnology Advances: Hidden antibiotics: Where to uncover?[…]
In De Standaard verscheen dit weekend (6 en 7 oktober 2018) een artikel over de huidige problemen rond pastic vervuiling en hoe de industrie er momenteel mee omgaat. Ook professor Soetaert mocht zijn mening geven over dit actuele probleem. U kan het volledige nieuwsartikel hier terugvinden.
‘Classical’ biosurfactants produced by Starmerella bombicola contain oleic acid as the incorporated hydrophobic group. However, other chain lengths can (to a certain content) be incorporated by feeding the yeast with substrates of alternative chain lengths, be it with a lower efficiency. This is defined by the substrate specificity of the first enzymatic step in sophorolipid biosynthesis, Read more about New article published in Colloids and Interfaces on ‘Expression of Chimeric Cytochrome P450s’[…]
The AppliSurf INDUSTRY USER GROUP Kick-Off Event will be organised on 8 October 2018 at 9.30am in Ghent (Belgium). More information on this event can be found here. Registration is free but mandatory. Companies that wish to be involved in the user group can still join this VIS project by completing this form or contacting dr. Sophie Roelants.
Recently, our lab succeeded to produce bio-based glycolipid bolaamphiphile on a gram scale by using the genetically-engineered S. bombicola strain Δat Δsble Δfao1 (Van Renterghem et al., Biotechnol. Bioeng., 2018, 115, 1195–1206). This article show that the bio-based glyco-bolaamphiphile readily forms a hydrogel in water at room temperature, and that the hydrogel formation depends on the formation of self-assembled fibers. Here, you can find more information Read more about Article in ‘Soft Matter’ : Bio-based glyco-bolaamphiphile forms a temperature-responsive hydrogel with tunable elastic properties[…]