New article on applying food waste for sophorolipid production

This study evaluates the techno-economic feasibility of sophorolipid (SL) production process that co-utilizes food waste, glucose and oleic acid as substrates. Two variables are considered in terms of (a) Plant construction: Purchasing equipment either from the US or Mainland China and (b) Production: to produce SL crystals or a concentrated SL liquid/syrup. Hence, four scenarios Read more about New article on applying food waste for sophorolipid production[…]

Check our newest review on 5’UTRs!

Saccharomyces cerevisiae (baker’s yeast or brewer’s yeast) is a popular microbial host in industrial biotechnology. Most synthetic biology tools to tune pathway expression focus on controlling transcription, whereas post‐transcriptional regulation is often overlooked. In this review, we discuss regulatory elements found in the 5′ untranslated region (UTR) and their influence on protein synthesis. Next to Read more about Check our newest review on 5’UTRs![…]

Article: “Efficient in-situ separation design for long-term sophorolipids fermentation with high productivity”

Until now, the production of microbial biosurfactants has been limited to the use of first-generation (food) substrates. Moreover, the results on sophorolipids yield and productivity reported by state-of-the-art fed-batch processes for sophorolipids production remain unsatisfactory and lead to a significantly high cost per kg of the product. With an aim to address these problems, this Read more about Article: “Efficient in-situ separation design for long-term sophorolipids fermentation with high productivity”[…]

New article published on glucolipid synthesis in S. bombicola!

Glucolipids (GLs) are glycolipid biosurfactants with promising properties, but up until today these interesting molecules could only be produced using an engineered Starmerella bombicola strain(∆ugtB1::URA3 G9) producing GLs instead of sophorolipids, albeit with a very low average productivity (0.01 g/L.h). In this study, we found that all glycolipid biosynthetic genes and enzymes were downregulated in Read more about New article published on glucolipid synthesis in S. bombicola![…]

New article: ‘Production of long-chain hydroxy fatty acids by Starmerella bombicola’

Check our newest article in FEMS Yeast Research! In this article, the one-step microbial production of hydroxy fatty acids by S. bombicola was accomplished by the selective blockage of three catabolic pathways through metabolic engineering. Successful production of 17.39 g/l (ω-1) linked hydroxy fatty acids was obtained by the successive blockage of the sophorolipid biosynthesis, the Read more about New article: ‘Production of long-chain hydroxy fatty acids by Starmerella bombicola’[…]

Check our new book chapter in ‘Biobased Surfactants – 2nd Edition’

Biobased Surfactants: Synthesis, Properties, and Applications, Second Edition, covers biosurfactant synthesis and applications and demonstrates how to reduce manufacturing and purification costs, impurities, and by-products. Fully updated, this book covers surfactants in biomedical applications, detergents, personal care, food, pharmaceuticals, cosmetics, and nanotechnology. It reflects on the latest developments in biobased surfactant science and provides case Read more about Check our new book chapter in ‘Biobased Surfactants – 2nd Edition’[…]

Enroll now for online course on ‘Biobased Products for a Sustainable (Bio)economy’!

Have you ever asked what “biobased” means or wondered about the key aspects in developing and commercializing biobased products? This course will answer those questions and more; highlighting the opportunities, hurdles, and driving forces of the bioeconomy. Enroll now on the MOOC on ‘Biobased Products for a Sustainable (Bio)economy’!