Saccharomyces cerevisiae (baker’s yeast or brewer’s yeast) is a popular microbial host in industrial biotechnology. Most synthetic biology tools to tune pathway expression focus on controlling transcription, whereas post‐transcriptional regulation is often overlooked. In this review, we discuss regulatory elements…
Science Figured out: HMO’s@ InBio.be
Article: “Efficient in-situ separation design for long-term sophorolipids fermentation with high productivity”
Until now, the production of microbial biosurfactants has been limited to the use of first-generation (food) substrates. Moreover, the results on sophorolipids yield and productivity reported by state-of-the-art fed-batch processes for sophorolipids production remain unsatisfactory and lead to a significantly…
New article published on glucolipid synthesis in S. bombicola!
Glucolipids (GLs) are glycolipid biosurfactants with promising properties, but up until today these interesting molecules could only be produced using an engineered Starmerella bombicola strain(∆ugtB1::URA3 G9) producing GLs instead of sophorolipids, albeit with a very low average productivity (0.01 g/L.h).…
New article: ‘Production of long-chain hydroxy fatty acids by Starmerella bombicola’
Check our newest article in FEMS Yeast Research! In this article, the one-step microbial production of hydroxy fatty acids by S. bombicola was accomplished by the selective blockage of three catabolic pathways through metabolic engineering. Successful production of 17.39 g/l (ω-1)…